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Ingrid Laurendeau Selected Research

Plexiform Neurofibroma

10/2022VEGF and VEGFR family members are expressed by neoplastic cells of NF1-associated tumors and may play an oncogenic role in malignant peripheral nerve sheath tumor growth through an autocrine loop.
1/2018Involvement of Aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis.
6/2016Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells.
1/2014The activation of the WNT signaling pathway is a Hallmark in neurofibromatosis type 1 tumorigenesis.
7/2013MicroRNAome profiling in benign and malignant neurofibromatosis type 1-associated nerve sheath tumors: evidences of PTEN pathway alterations in early NF1 tumorigenesis.
11/2011Role of noncoding RNA ANRIL in genesis of plexiform neurofibromas in neurofibromatosis type 1.
3/2011SOX9 expression increases with malignant potential in tumors from patients with neurofibromatosis 1 and is not correlated to desert hedgehog.
1/2011Identification of genes potentially involved in the increased risk of malignancy in NF1-microdeleted patients.
1/2007Microarray-based identification of tenascin C and tenascin XB, genes possibly involved in tumorigenesis associated with neurofibromatosis type 1.
7/2004Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1, based on large-scale real-time RT-PCR.
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Ingrid Laurendeau Research Topics

Disease

20Neoplasms (Cancer)
10/2022 - 03/2002
11Plexiform Neurofibroma
10/2022 - 06/2004
9Carcinogenesis
10/2022 - 03/2002
8Neurofibrosarcoma (MPNST)
10/2022 - 06/2004
4Neurofibroma
10/2022 - 06/2004
4Neurofibromatosis 1 (Neurofibromatosis Type I)
01/2016 - 01/2007
4Ischemia
03/2011 - 12/2007
4Hepatocellular Carcinoma (Hepatoma)
01/2007 - 10/2003
3Breast Neoplasms (Breast Cancer)
12/2010 - 03/2002
3Fibrosis (Cirrhosis)
12/2005 - 01/2005
2Metachromatic Leukodystrophy (Sulfatide Lipidosis)
06/2015 - 01/2006
2Demyelinating Diseases (Demyelinating Disease)
06/2015 - 01/2006
2Meningioma (Meningiomas)
07/2010 - 07/2009
2Carcinoma (Carcinomatosis)
10/2008 - 09/2007
2Liver Diseases (Liver Disease)
09/2008 - 01/2005
2Rheumatic Diseases (Rheumatism)
04/2007 - 09/2005
2Cryoglobulinemia
04/2007 - 09/2005
2Vasculitis (Vasculitides)
04/2007 - 09/2005
2Polyarteritis Nodosa (Periarteritis Nodosa)
04/2007 - 09/2005
2Neoplasm Metastasis (Metastasis)
01/2007 - 04/2006
1Nerve Sheath Neoplasms (Nerve Sheath Neoplasm)
06/2016
1Lysosomal Storage Diseases (Lysosomal Storage Disease)
06/2015
1Paraganglioma (Paragangliomas)
12/2012
1Pheochromocytoma
12/2012
1Cholestasis
03/2012
1progressive familial intrahepatic 1 Cholestasis
03/2012
1Intrahepatic Cholestasis of Pregnancy
03/2012
1Cholelithiasis
03/2012
1Sarcoma (Soft Tissue Sarcoma)
03/2011
1Churg-Strauss Syndrome (Allergic Angiitis)
11/2010
1Neurofibromatoses (Neurofibromatosis)
01/2010
1Necrosis
02/2009
1Urinary Bladder Neoplasms (Bladder Cancer)
10/2008
1Chronic Hepatitis C
09/2008
1Vascular Diseases (Vascular Disease)
04/2008
1Insulin Resistance
02/2008
1Vision Disorders (Hemeralopia)
12/2007
1Ischemic Stroke
12/2007
1Melanoma (Melanoma, Malignant)
04/2007
1Glioma (Gliomas)
01/2007
1Body Weight (Weight, Body)
01/2007

Drug/Important Bio-Agent (IBA)

10Messenger RNA (mRNA)IBA
03/2011 - 03/2002
7Proteins (Proteins, Gene)FDA Link
10/2022 - 06/2004
6RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
10/2008 - 03/2002
4Biomarkers (Surrogate Marker)IBA
03/2011 - 11/2003
4CytokinesIBA
11/2010 - 06/2004
3Transcription Factors (Transcription Factor)IBA
03/2011 - 06/2004
3Matrix Metalloproteinases (MMPs)IBA
04/2007 - 04/2006
2Adenosine Triphosphate (ATP)IBA
06/2016 - 03/2012
2DNA (Deoxyribonucleic Acid)IBA
01/2016 - 12/2012
2Cerebroside-Sulfatase (Arylsulfatase A)IBA
06/2015 - 01/2006
2MicroRNAs (MicroRNA)IBA
07/2013 - 01/2011
2Untranslated RNA (Noncoding RNA)IBA
11/2011 - 04/2007
2matrigelIBA
12/2010 - 04/2008
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2009 - 09/2005
2Uroplakin IIIBA
10/2008 - 09/2007
2tributyl phosphate (TBP)IBA
10/2008 - 09/2007
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2022
1Nonsense Codon (Nonsense Mutation)IBA
07/2020
1Small Interfering RNA (siRNA)IBA
01/2018
12-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amideIBA
01/2018
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
01/2018
1ChromatinIBA
01/2017
1Sirolimus (Rapamycin)FDA Link
06/2016
1Mechanistic Target of Rapamycin Complex 2IBA
06/2016
1Mechanistic Target of Rapamycin Complex 1IBA
06/2016
1(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA
06/2016
1antineoplaston A10 (A 10)IBA
01/2016
1Phospholipids (Phosphatides)FDA LinkGeneric
03/2012
1Oral ContraceptivesIBA
03/2012
1Thrombospondin 1IBA
03/2011
1von Willebrand FactorIBA
12/2010
1Interleukin-17 (Interleukin 17)IBA
11/2010
1Biological ProductsIBA
07/2010
1ErbB Receptors (EGF Receptor)IBA
07/2009
1LigandsIBA
07/2009
1Colony-Stimulating Factors (Colony Stimulating Factor)IBA
02/2009
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
02/2009
1InterleukinsIBA
02/2009
1Alanine Transaminase (SGPT)IBA
09/2008
1Interleukin-8 (Interleukin 8)IBA
09/2008
1erucylphosphocholineIBA
04/2008
1Phosphatidylinositols (Phosphatidylinositol)IBA
02/2008
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
02/2008
1Insulin (Novolin)FDA Link
02/2008
1Retinaldehyde (Retinal)IBA
12/2007
1Fluorescein (Funduscein)FDA LinkGeneric
12/2007
1RNA (Ribonucleic Acid)IBA
09/2007
1Protein Isoforms (Isoforms)IBA
09/2007
1TATA-Box Binding Protein (TATA-Binding Protein)IBA
09/2007
1Tumor Suppressor Protein p14ARF (p14ARF)IBA
04/2007
1Interleukin-1beta (Interleukin 1 beta)IBA
04/2007
1AntibodiesIBA
01/2007
1TenascinIBA
01/2007
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2007
1Pravastatin (Pravachol)FDA LinkGeneric
01/2007

Therapy/Procedure

10Therapeutics
01/2018 - 02/2005
1Injections
03/2011
1Surgical Amputation (Amputations)
12/2008
1Cell- and Tissue-Based Therapy (Cell Therapy)
04/2008